The following interventions are to be made-  Patients fulfilling the inclusion criteria will be included.  The marked physical appearance of the patient will be noted.  Proper case taking.  Totality of the case will be formed including the physical appearance.  QOLI assessment will be done at entry using QOLI Scale.  Selection of medicine.  Prescription will be done (4globules of 40 no. size of the 30th potency twice daily, followed by placebo.)  The patient is called for follow-up after 2 weeks.  Improvement will be assessed. ● If the patient shows improvements- placebo is continued. ● If the patient does not show any amelioration/improvement— ◦ Placebo is continued for another 2 weeks. ◦ 4globules of 40 no. size of the 200th potency twice daily is prescribed and the patient is called for follow-up after 1 month. ◦ If still no improvement is seen 4globules of 40 no. size of the 1M potency twice daily is prescribed and the patient is called for follow-up after 1 month. ◦ If still no improvement is seen then the case will marked as not improved.  After 6 months of follow-up QOLI assessment will be done.  Results will be analyzed after the completion of study and represented by using appropriate statistical methods.